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Molecular Biology and Bioinformatics Glossary

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K

K

A statistical parameter used in calculating BLAST scores that can be thought of as a natural scale for search space size. The value K is used in converting a raw score (S) to a bit score (S'). (NCBI)

Karyotype

A photomicrograph of an individual's chromosomes arranged in a standard format showing the number, size, and shape of each chromosome type; used in low-resolution physical mapping to correlate gross chromosomal abnormalities with the characteristics of specific diseases. (ORNL)

Kilobase (kb)

Unit of length for DNA fragments equal to 1000 nucleotides. (ORNL)

Knockout

Deactivation of specific genes; used in laboratory organisms to study gene function.
See also: gene, locus, model organisms (ORNL)

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